Artikel
CT-MIBI-SPECT image fusion detects abnormal parathyroid adenomas in patients with goitre
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Veröffentlicht: | 23. April 2012 |
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Gliederung
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Introduction: The aim of this study was to evaluate whether CT-MIBI-SPECT image fusion is superior to MIBI-SPECT and CT alone in detecting abnormal parathyroid glands in patients with hyperparathyroidism and concomittant goitre.
Materials and methods: CT-MIBI-SPECT image fusion was performed in 40 patients who had to be operated on for hyperparathyroidism and concomittant goitre. CT-MIBI-SPECT image fusion results were compared with CT and MIBI-SPECT alone. The predicted positions were correlated with intraoperative findings.
Results: CT-MIBI-SPECT image fusion was able to predict the exact position of all abnormal glands per patient in 75% of patients, whereas CT alone succeeded in 45% and MIBI-SPECT alone in 50%. In all patients simultaneous thyroidectomy had to be performed. Overall accuracy for CT-MIBI-SPECT image fusion was 92,0%, for CT alone 84,0%, for MIBI-SPECT 83,0%.
Conclusion: This study shows that CT-MIBI-SPECT image fusion is superior to CT or MIBI-SPECT alone for preoperative localization of abnormal parathyroid glands in patients with hyperparathyroidism and goitre.