Artikel
Endovascular treatment of unruptured cerebral aneurysms using Guglielmi detachable coils
Endovaskuläre Behandlung von nicht-rupturierten zerebralen Aneurysmen mit Platinspiralen
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Autoren
Veröffentlicht: | 23. April 2004 |
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Gliederung
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Objective
Endovascular embolisation of intracranial aneurysms using Guglielmi electrolytically detachable coils (GDC) is a treatment option to microsurgical clipping. We report our results with this technique in the treatment of unruptured aneurysms.
Methods
Since February 1992 176 unruptured aneurysms (ACI 77, ACA 5, ACoA 24, MCA 33, BA 26, VA 7, PCA 4) in 155 patients were treated at the Vienna General Hospital using GDCs. The mean age of the treated patients was 52 ± 11 yrs (range 26 to 76 yrs), there were 43 male and 112 female patients. 25 % of patients had a previous SAH from another aneurysm, 15 % became symptomatic due to mass effect, in all other patients (60 %) the aneurysm was found incidentally. Clinical follow-up is available from 95 % of the patients.
Results
Almost all patients had an excellent outcome. There was a low procedure related permanent morbidity, there was no treatment related mortality. The most frequent complication were thromboembolic events during the intervention (11.4 %), from these 3 patients (1.7 %) suffered a stroke (2 mild / 1 severe disability), the other patients kept asymptomatic or had a TIA (7.4 %), 1.1 % had a PRIND. Aneurysm perforation with the guide wire during intervention occurred in 2 patients resulting in SAH in one, both patients recovered without neurological deficit. In another patient (0.57%) the aneurysms ruptured during embolisation leading to relevant neurological disability. In 3 patients with a partially thrombosed giant aneurysm palliative GDC embolisation could not prevent them from later aneurysm rupture, otherwise there was no aneurysm rupture in all other patients in the follow-up period to our knowledge so far. In 12.5 % of patients a re-embolisation was performed, in 4.5 % sufficient obliteration could not be achieved and subsequent microsurgical clipping was done.
Conclusions
We feel that GDC embolisation of unruptured aneurysms is a safe procedure with low intervention related morbidity. It seems to give good protection against future SAH, long-term follow-up studies will have to confirm this.