Artikel
Surgery of Graves' disease – A 10 year review
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Veröffentlicht: | 20. Mai 2011 |
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Gliederung
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Introduction: Surgical treatment of Graves' disease has changed over the last decade from Dunhills operation to total thyroidectomy as the standard operative procedure.
Materials and methods: Prospective analysis of 207 patients (81% female, 19% male)having been operated between 2000 and 2009 in our clinic.
Results: Today thyroidectomy has become the standard operative procedure (85 % in 2008 vs. 20% in 2000). Median age at time of surgery was 42.7 years (±13.6 y). Endocrine orbitopathy preoperativly was diagnosed in 48.5%.
Postoperative hypocalcaemia was found in 7.1% and recurrent laryngeal nerve paralysis in 1.7% of patients. The incidences of theses complications were not different between different types of operation. There was no recurrence of Grave´s disease after surgery. No patient needed additional radioiodine therapy.
Conclusion: Thyroidectomy is nowadays the standard treatment of Graves' disease in our department. It is an effective and safe way to treat hyperthyroidism. Postoperative hypoparathyroidism is the most noteworthy complication.